12Α

Clean Enzymatic Oxidation of 12α‐Hydroxysteroids to 12‐Oxo ...

1 Apr 2019 ... Abstract The C12 specific oxidation of hydroxysteroids is an essential reaction required for the preparation of pharmaceutical ingredients like ...

12α

Human insulin resistance is associated with increased plasma ...

24 Jul 2013 ... Human insulin resistance is associated with increased plasma levels of 12α- hydroxylated bile acids. Haeusler RA(1), Astiarraga B, Camastra S, ...

12α

Structure Database (LMSD)

Results 1 - 50 of 201 ... LM_ID, Common Name, Systematic Name, Formula, Mass. LMST04030001, -, 3α ,7α,12α-trihydroxy-5β-cholestan-26- oic acid, C27H46O5 ...

12α

Metabolism of Oxo-Bile Acids and Characterization of Recombinant ...

15 May 2019 ... Metabolism of Oxo-Bile Acids and Characterization of Recombinant 12α- Hydroxysteroid Dehydrogenases from Bile Acid 7α-Dehydroxylating ...

12α

Sensitive analysis of serum 3α, 7α, 12α,24-tetrahydroxy-5β ...

The CoA esters of diastereomeric 3α,7α,12α,24-tetrahydroxy-5β-cholest-26-oic acid were separated by HPLC exactly as described in detail (16) to guarantee ...

12α

On the Properties of the 12α‐Hydroxylase in Cholic Acid Biosynthesis

The 12α‐hydroxylation of the steroid nucleus in cholic acid biosynthesis was studied in the microsomal fraction of rat liver homogenate. The reaction was shown ...

12α

Suppression of sterol 12α-hydroxylase transcription by the short ...

1 Oct 2001 ... Abstract. Cholesterol conversion to bile acids is subject to a feedback regulatory mechanism by which bile acids down-regulate their own ...

12α

α1-Fetoprotein Transcription Factor Is Required for the Expression of ...

9 Jun 2000 ... Sterol 12α-hydroxylase/CYP8b1 is the specific enzyme required for cholic acid synthesis. The levels of this enzyme determine the ratio of cholic ...

12α

The biosynthesis of 12α-hydroxylated gibberellins in a cell-free ...

A previously unknown pathway for the biosynthesis of 12α-hydroxylated gibberellins was found in a cell-free system from Cucurbita maxima endosperm.

12α

Expression of sterol 12α-hydroxylase alters bile acid pool ...

Background & Aims: The rate of 12α-hydroxylation of bile acid intermediates is believed to determine the ratio of cholic acid (CA) to chenodeoxycholic acid ...

12α

23-NOR-5β-CHOLANIC ACID-3α, 12α-DIOL DIACETATE, METHYL ...

Catalogue ID N2060-000 CAS No CH Groups C28 H44 Deuterated? No Formula C28 H44 O6 Light Sensitive? No Melting Point 157-1458ºC Min. Quantity ...

12α

Distinct Binding of Cholesterol and 5β-Cholestane-3α,7α,12α-triol to ...

21 Mar 2006 ... Distinct Binding of Cholesterol and 5β-Cholestane-3α,7α,12α-triol to Cytochrome P450 27A1: Evidence from Modeling and Site-Directed ...

12α

5β-CHOLANIC ACID-3α, 12α-DIOL N-(2-SULPHOETHYL)-AMIDE ...

5β-CHOLANIC ACID-3α, 12α-DIOL N-(2-SULPHOETHYL)-AMIDE from Steraloids. For over 60 years, we've supplied the finest research institutions, ...

12α

Notes- Synthesis of Coprostane-3α, 7α, 12α-triol-27-C14 ...

Notes- Synthesis of Coprostane-3α, 7α, 12α-triol-27-C14, Coprostane-3α, 7α, 12α,-triol-24-one-27-C14, and Coprostane-3α, 7α, 12α, 24-tetrol-27-C14.

12α

23-NOR-5β-CHOLANIC ACID-3α, 12α-DIOL METHYL ESTER ...

23-NOR-5β-CHOLANIC ACID-3α, 12α-DIOL METHYL ESTER from Steraloids. For over 60 years, we've supplied the finest research institutions, pharmaceutical  ...

12α

C23 bile acids, alcohols, and derivatives [ST0406]

LM_ID, Common Name, Systematic Name, Formula, Mass. LMST04060001, -, 24 -Nor-5β-cholane-3α,7α,12α,22,23- pentol, C23H40O5, 396.2876.

12α

Molecular Cloning and Expression of Rabbit Sterol 12α-Hydroxylase

13 Dec 1996 ... Sterol 12α-hydroxylase is an important enzyme in bile acid biosynthesis, responsible for the balance between formation of cholic acid and ...

12α

Two new 11α,12α-epoxy-ursan-28,13β-olides and other triterpenes ...

Three new triterpenes, 2α-acetoxy-3β,19α-dihydroxy-11α,12α-epoxy-ursan-28, 13β-olide, 3β-acetoxy-2α,19α-dihydroxy-11α,12α-epoxy-ursan-28,13β-olide and  ...

12α

12-Oxygenated pregnane derivatives. Part I. (a) 21-Acetoxy-12α ...

12-Oxygenated pregnane derivatives. Part I. (a) 21-Acetoxy-12α : 17α- dihydroxypregn-4-ene-3 : 20-dione; (b) 12α : 21-diacetoxy-17α-hydroxypregn-4- ene-3 ...

12α

The Absorption of Orally Administered [12α-3H]Digoxin in Man ...

[12α-3H]Digoxin and polyethylene glycol (nonabsorbable marker) dissolved in water were administered orally to five healthy subjects. 2. The ratio between the ...

12α

The gastrointestinal uptake of methyldigoxin-12α-3H in man ...

Methyldigoxin-12α-3H and the nonabsorbable marker polyethylene glycol (PEG) were administered orally to five healthy subjects. Comparison of the ...

12α

Comparison of Solubilization Capacity of Resveratrol in Sodium 3α ...

22 Oct 2013 ... Comparison of Solubilization Capacity of Resveratrol in Sodium 3α,12α- Dihydroxy-7-oxo-5β-cholanoate and Sodium Dodecyl Sulfate.

12α

3α,12α-Dihydroxy-5β-pregnan-20-one 3,12-diacetate

3α,12α-Dihydroxy-5β-pregnan-20-one 3,12-diacetate; CAS No.:15991-93-2. Buy from Sigma-Aldrich.

12α

Human Insulin Resistance Is Associated With Increased Plasma ...

Human Insulin Resistance Is Associated With Increased Plasma Levels of 12α- Hydroxylated Bile Acids. Rebecca A. Haeusler⇑,; Brenno Astiarraga,; Stefania ...

12α

Formation of bile acids in man: conversion of cholesterol into ... - JCI

Formation of bile acids in man: conversion of cholesterol into 5β-cholestane-3α, 7α,12α-triol in liver homogenates. Ingemar Björkhem, Henry Danielsson, Kurt ...

12α

Synthesis of cyclo-bis [7α, 12α-diacetoxy-3β-dicyanomethyl-3α-(4 ...

A second 'cholaphane' framework is manifested in the title compound , which has been prepared from methyl 3α,7α, 12α-triacetoxycholanoate in 23% overall ...

12α

Temporal changes in bile acid levels and 12α-hydroxylation after ...

20 Jan 2019 ... A significant increase in the 12α-hydroxylated/non12α-hydroxylated BA ratio during fasting and postprandially at 2 years, but not 1 month, post ...

12α

Stereochemistry in dehydrogenation of 3α, 7α, 12α-trihydroxy-5β ...

Stereochemistry in dehydrogenation of 3α, 7α, 12α-trihydroxy-5β-cholestan-26- oyl CoA during cholic acid biosynthesis. Masatoshi Yuri, Noriyuki Hara, Yoshinori  ...

12α

CONFIGULATION AT C-23 IN 5β-CHOLESTANE-3α, 7α, 12α, 23 ...

The configuration at C-23 in 5β-cholestane-3α, 7α, 12α, 23-tetrol, one of the bile alcohols isolated from the bile and feces of patients with cerebrotendinous ...

12α

(PDF) Sterol 12α-hydroxylase Aggravates Dyslipidemia by ...

20 Jan 2020 ... PDF | Sterol 12α-hydroxylase (CYP8B1) is required for the synthesis of cholic acid in the classic bile acid synthesis pathway and plays a role in.

12α

12α-hydroxysteroid dehydrogenase

15 Jun 2010 ... The gene encoding this 12α-hydroxysteroid dehydrogenase from the human intestinal bacterium Clostridium sp. ATCC 29733 has not been ...

12α

(20R,24R,25S)-3α,7α,12α,27-Tetra-acet-oxy-24,26-ep-oxy-5β ...

In the title anhydro-scymnol tetra-acetate, C(35)H(54)O(9), the fused chair conformation of the cyclo-hexane A/B ring junction is cis with a 5β-H configuration.

12α

Prevention of fatty liver by dietary intervention via regulation of 12α ...

25 Sep 2019 ... Prevention of fatty liver by dietary intervention via regulation of 12α-hydroxylated bile acid metabolism : Studies on oligosaccharide and dairy ...

12α

Crystal structure of 12α-hydroxy-2, 3, 9-trimethoxy-12-oxo-6, 6α, 12 ...

11 Feb 2014 ... Citation Information: Zeitschrift für Kristallographie - New Crystal Structures, Volume 225, Issue 2, Pages 374–376, ISSN (Online) 2197-4578, ...

12α

CHEBI:16466

17 Mar 2019 ... ChEBI Name, 3α,7α,12α-trihydroxy-5β-cholestan-26-al. ChEBI ID, CHEBI:16466. ChEBI ASCII Name, 3alpha,7alpha ...

12α

CXC chemokine ligand 12α-mediated increase in insulin secretion ...

CXC chemokine ligand 12α-mediated increase in insulin secretion and survival of mouse pancreatic islets in response to oxidative stress through modulation of ...

12α

7α,12α-Dihydroxycholest-4-en-3-one-d7

Buy 7α,12α-Dihydroxycholest-4-en-3-one-d7 (CAS 1254-03-1 (unlabeled)), a biochemical for proteomics research, from Santa Cruz. MW: 423.68.

12α

5β,7α,12α,17α

Structure, properties, spectra, suppliers and links for: (5β,7α,12α,17α)-7,12- Dihydroxy-3-oxocholan-24-oic acid.

12α

Ordered magnetism in the intrinsically decorated jeff=12α ... - scanR

5 Dec 2019 ... The antiferromagnetic mixed valence ternary oxide α-CoV3O8 displays disorder on the Co 2+ site that is inherent to the Ibam space group ...

12α

Methyl 3α-azido-7α-acetoxy-12α-[4-(N,N-dimethylamino)benzoyloxy]

Structure, properties, spectra, suppliers and links for: Methyl 3α-azido-7α-acetoxy -12α-[4-(N,N-dimethylamino)benzoyloxy]-5β-cholan-24-oate.

12α

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